News

Introducing clinical partners: SEIN

Stichting Epilepsie Instellingen Nederland (SEIN), a renowned expertise center for epilepsy and sleep medicine, is making significant strides in advancing the care of epilepsy patients. With two state-of-the-art clinics in Heemstede and Zwolle, alongside twelve outreach outpatient clinics across the northern Netherlands, SEIN provides top-tier multidisciplinary care with cutting-edge video-EEG diagnostics.


As a key partner in the RELIEVE project, SEIN is poised to play a critical role in validating the AI approach to detecting and predicting epileptic seizures. SEIN collaborates through their Epilepsy Monitoring Unit (EMU), consenting presurgical evaluation patients to share anonymized and annotated EEG data for testing the AI algorithms. This effort, part of the SALIENT study, will demonstrate the feasibility of a new wearable sensor for long-term ambulatory recordings that apply the AI algorithms.
Dr. Thijs, who leads SEIN’s involvement in RELIEVE, shares the motivation behind their work on seizure prediction: “Seizure prediction is a pressing need. The unpredictability of seizures significantly contributes to the burden of the disease, and reliable prediction methods could revolutionize epilepsy care.”
With a long history of clinical epilepsy research and the validation of cortical excitability as novel biomarkers, SEIN’s EMU is well-positioned to advance seizure detection. SEIN leads the brain@home consortium, a public-private collaboration aimed at developing reliable biomarkers for epilepsy and migraine through brain activity monitoring in home settings.
Dr. Thijs, the leader of RELIEVE at SEIN, brings a wealth of expertise to the project. As an academic neurologist and clinical leader specializing in epilepsy and autonomic disorders, Dr. Thijs holds several prestigious positions, including Clinical Director at SEIN, Senior Clinical Lecturer at Leiden University Medical Centre, and Honorary Research Associate at the Queen Square Institute of Neurology in London. With over 200 peer-reviewed publications to his name, Dr. Thijs and his team have made groundbreaking contributions to epilepsy care, particularly in their research on nocturnal seizures and SUDEP (sudden unexpected death in epilepsy).